Cell reportsAnimalsSinoatrial NodeMuscleSmoothVascular
Distinct populations of vascular smooth muscle and sinoatrial progenitors are localized adjacent to pro-epicardium.
Lianjie Miao, Anika Nusrat, Jian Li, Changhong Yin, Yangyang Lu, Xianyan Kuang, Daizong Sun, Edward Lo, Renjie Song, Weihua Huang, Xiaochun Long, Bradley K McConnell, Harold A Singer, Robert J Schwartz, Preethi Gunaratne
Published: 202510.1016/j.celrep.2025.116580
Abstract
The developmental potential of cells adjacent to pro-epicardial (PE) cells (pro-EpiCs) that also express pro-EpiC markers is unknown. We apply single-cell mRNA deep sequencing paired with RNAScope validation, bioinformatic analysis, and lineage traci…
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