Cell reportsAnimalsAxonsReceptorsGABA-ADopaminergic Neurons
Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum.
Samuel G Brill-Weil, Paul F Kramer, Anthony Yanez, Anna M Lipkin, Faye H Clever, Renshu Zhang, Zayd M Khaliq
Published: 202510.1016/j.celrep.2025.116555
Abstract
Axons of dopaminergic neurons express gamma-aminobutyric acid type-A receptors (GABAARs) and nicotinic acetylcholine receptors (nAChRs), which are positioned to shape striatal dopamine release. We examine how interactions between GABAARs and nAChRs i…
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