Cell reportsMycobacterium bovisHexokinaseMitochondriaAnimalsMacrophages
Mycobacterium bovis induces macrophage mitochondrial release of hexokinase 2 to enhance intracellular survival.
Lin Li, Yulan Chen, Yuanzhi Wang, Yuhui Dong, Haoran Wang, Ziyi Liu, Xin Ge, Puxiu Shen, Yue Li, Dingpu Liu, Xiangmei Zhou
Published: 202510.1016/j.celrep.2025.116421
Abstract
Hexokinases (HKs) are essential enzymes in sugar metabolism, but their mitochondrial release also reflects cellular status in disease. Mycobacterium bovis (M. bovis), the causative agent of bovine and human tuberculosis, infects macrophages and induc…
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