Cell reportsAnimalsMicrogliaObesityDietHigh-Fat
Time-restricted feeding provides limited microglial immunometabolic improvements in diet-induced obese rats.
Han Jiao, Jarne Jermei, Xian Liang, Hendrik J P van der Zande, Frank Vrieling, Valentina Sophia Rumanova, Milan Dorscheidt, Anhui Wang, Ewout Foppen, Bob Ignacio, Dirk Jan Stenvers, Tiemin Liu, Kimberly Bonger, Rinke Stienstra, Zhi Zhang
Published: 202510.1016/j.celrep.2025.116380
Abstract
Time-restricted eating has shown great promise for improving metabolic health in humans with obesity, but its mechanism is still not completely resolved. In this study, we investigated how time-restricted feeding (TRF) affects microglial immunometabo…
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