Cellular signallingAnimalsTOR Serine-Threonine KinasesOxidative StressApoptosisProto-Oncogene Proteins c-akt
Cordycepin alleviates sepsis-induced cardiomyopathy by attenuating mitochondrial oxidative stress and apoptosis through modulation of the PI3K/Akt/mTOR pathway.
Qian Yu, Zilin Liu, Jiangtao Yu, Haoli Ma, Yijie Wang, Feihong Yang, Gang Li, Ling Chen, Cheng Jiang
Published: 202610.1016/j.cellsig.2026.112354
Abstract
OBJECTIVE: Sepsis-induced cardiomyopathy (SICM) is a frequent and life-threatening complication of sepsis, characterized by acute cardiac dysfunction and high mortality, yet no specific therapy is currently available. Cordycepin (COR), a natural bioa…
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