Cellular signallingHumansGliomaWnt Signaling PathwayAnimalsCell Line
Selenoprotein P drives glioma malignancy via LRP8-dependent activation of Wnt/β-catenin signaling.
Xiaoke Wu, Yao Zhang, Guang Rong, Zixiao Zhang, Jieyu Jin, Junchao Feng, Haiyang Wu, Yin Wang
Published: 202610.1016/j.cellsig.2025.112341
Abstract
Glioma is a highly aggressive central nervous system malignancy with poor prognosis and limited therapeutic options. Selenoprotein P (SeP) plays key roles in the nervous system, but its function in glioma remains unclear. Analysis of TCGA and CGGA da…
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