Cellular signallingAnimalsPyroptosisSepsisCardiomyopathiesMice
Interferon regulatory factor 1 promotes pyroptosis and inflammation in mouse sepsis-induced cardiomyopathy.
Meng-Qin Pei, Ya-Fen Zeng, Yu-Shen Yang, Yu-Ming Fang, Shu Lin, Jin-Wei Liang, He-Fan He
Published: 202610.1016/j.cellsig.2025.112332
Abstract
Although pyroptosis is involved in sepsis and sepsis-induced cardiomyopathy (SIC), the underlying mechanism remains unclear. This study aimed to investigate the role and mechanims of myocardial pyroptosis in the progression of SIC. We first identifie…
Preview only. Read the full abstract at the source