Cellular signallingAnimalsPyroptosisMiceInfrared RaysTRPV Cation Channels
Far-infrared irradiation suppresses pyroptosis in ischemic flaps through TRPV3-mediated activation of the A2AR/EPAC1/Rap1 signaling pathway.
Yuqi Wang, Jiaying Lou, Rongfang Dai, Liang Chen, Yi Wang, Yu Wang, Xiangwei Ling, Xiaoqiong Jiang, Fuman Cai
Published: 202610.1016/j.cellsig.2025.112299
Abstract
Random pattern skin flaps (RPSFs) are often associated with distal ischemic necrosis, primarily due to inadequate blood perfusion. Although far-infrared (FIR) irradiation has been reported to promote tissue repair, its precise role and underlying mec…
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