Cellular signallingHumansApoptosisPancreatic NeoplasmsMitochondriaAnimals
OCIAD2-IQGAP1 interaction promotes pancreatic cancer progression by suppressing oxidative stress and mitochondria-mediated apoptosis.
Zhenyan Pan, Lingming Kong, Fengyu Shi, Kongjie Ying, Haonan Xie, Xiulin Wu, Ganglian Lin, Jiangqiao Yao, Ziyan Chen, Yi Wang, Gang Chen, Qiandong Zhu
Published: 202610.1016/j.cellsig.2025.112217
Abstract
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) ranks among the foremost causes of cancer-associated mortality globally, with a 5-year survival rate of less than 10 %. Ovarian carcinoma immunoreactive antigen domain containing 2 (OCIAD2), which h…
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