Cellular signallingHumansFerroptosisNeoplasmsMethyltransferasesAnimals
Ferroptosis modulation by METTL14 in cancers: From molecular insights to therapeutic strategies.
Boran Huang, Chenglin Zhu, Xinyu Zhang, Qi Zhang, Honggang Wang
Published: 202610.1016/j.cellsig.2025.112212
Abstract
Ferroptosis is an iron-dependent, lipid peroxidation-driven form of regulated cell death that is mechanistically distinct from apoptosis and necrosis. In cancer, it plays a dual role: it can act as a tumor suppressor mechanism, yet may also contribut…
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