Cellular signallingHumansSTAT3 Transcription FactorSnail Family Transcription FactorsLung NeoplasmsAnimals
RIPK2/STAT3 signaling axis drives lung cancer metastasis through SNAIL activation: Molecular mechanisms and clinical implications.
Wei Liu, Peng Luo, Xiaoliang Ji, Hongwei Cui, Mingming Zheng, Fangshuo Liu, Hongfei Liu
Published: 202610.1016/j.cellsig.2025.112211
Abstract
BACKGROUND: Lung adenocarcinoma is the most common histological subtype of lung cancer with high metastatic propensity. Epithelial-mesenchymal transition (EMT) plays a crucial role in tumor metastasis, but the molecular mechanisms remain incompletely…
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