Cellular signallingNucleotidyltransferasesHumansNasopharyngeal CarcinomaDNA DamageMembrane Proteins
RFC5 enhances DNA damage response and immune escape via suppressing the cGAS-STING pathway in nasopharyngeal carcinoma.
Yumo Han, Mengyu Miao, Ying Shan, Yong Zhou, Si Pan, Rui Zhu, Ling Yuan, Ziyu Zhu, Jie Zhang
Published: 202610.1016/j.cellsig.2025.112210
Abstract
The capacity of tumor cells to repair DNA damage is closely associated with their resistance to radiotherapy and chemotherapy. Our investigation demonstrated elevated RFC5 levels within nasopharyngeal carcinoma (NPC) cells and is involved in DNA dama…
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