Cellular signallingHumansGoblet CellsColorectal NeoplasmsSingle-Cell AnalysisCarcinogenesis
Single-cell sequencing analysis reveals CHURC1 as a non-canonical oncoprotein governing goblet cell-driven colorectal tumorigenesis.
Fei Qian, Min Jiang, Weilin Pu, Jianfeng Zhang, Zhao Zhang, Youlang Zhou, Keke Shao, Weifeng Ding
Published: 202610.1016/j.cellsig.2025.112197
Abstract
Colorectal cancer (CRC) is a type of malignant tumor with an incompletely understood etiology, particularly concerning the specific cellular origins that trigger tumorigenesis. The precise cells that initiate the cancer transformation within the comp…
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