Cellular signallingAnimalsMicroRNAsNLR FamilyPyrin Domain-Containing 3 ProteinRNA
Mechanistic insights into homocysteine-induced coronary microcirculatory dysfunction post-MI: The pivotal role of LncMEG3/miR-223/NLRP3 signaling axis.
Jingan Rao, Congcong Ding, Xiao Huang, Junpei Li, Jine Liu, Zikang Cheng, Huihong Zeng, Biming Zhan, Xiaoshu Cheng
Published: 202510.1016/j.cellsig.2025.112164
Abstract
BACKGROUND: Hyperhomocysteinemia (HHcy) is known to exacerbate coronary microvascular dysfunction in patients experiencing acute myocardial infarction (AMI). However, the precise mechanisms underlying the exacerbation of injury by HHcy remain to be f…
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