Cellular signallingMaleHumansPhenylthiohydantoinNitrilesSTAT3 Transcription Factor
PPP1R14B promotes the progression of prostate cancer by regulating the JAK2/STAT3/AR pathway and alters the sensitivity and resistance to enzalutamide.
Long Cheng, Chengyu You, Longtu Ma, Shuai Liu, Yongfeng Lao, Xin Guan, Wenyun Wang, Xi Xiao, Yan Tao, Zhilong Dong
Published: 202510.1016/j.cellsig.2025.112163
Abstract
Prostate cancer (PCa) is the tumor with the highest incidence rate among men worldwide. There is still a lack of effective treatment options for metastatic PCa and castration-resistant prostate cancer (CRPC). Protein phosphatase 1 regulatory subunit…
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