Cell
Structure of pancreatic hIAPP fibrils derived from patients with type 2 diabetes.
Wenjing Liu, Jianting Han, Wei Gong, Fei Zhang, Qin Cao
Published: 202610.1016/j.cell.2025.12.001
Abstract
Type 2 diabetes (T2D) impacts the quality of life and lifespan of nearly 10% of the global population. Human islet amyloid polypeptide (hIAPP) constitutes a major component of islet amyloid deposition in patients with T2D, with hIAPP fibrils believed…
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