CellHumansFemalePregnancyHematopoietic Stem CellsImmune System
Systemic immune activity occurs during human immune system maturation.
Shuai He, Chun-Ling Luo, Tao Luo, Hai-Tian Chen, Shao-Feng Zhang, Jia-Xin Jiang, Xiao-Yi Wang, Dong Ma, Shuang-Lian Zhao, An-Yi Xu, Jing-Jing He, Zhao-Hui Ruan, Wen-Xin Yan, Zi-Hao Xu, Yang Liu
Published: 202510.1016/j.cell.2025.10.003
Abstract
The second trimester of pregnancy is a pivotal stage in human immune system development. Utilizing single-cell RNA sequencing and T cell receptor sequencing, we profiled 2,868,420 immune cells from 321 samples across 23 organs, including adult tissue…
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