CellAnimalsMiceHumansImmunologic SurveillanceCalcitonin Gene-Related Peptide
Cancer cells co-opt an inter-organ neuroimmune circuit to escape immune surveillance.
Yu Zhang, Yibo Guo, Zheqi Liu, Yiting Sun, Xi Yang, Mingtao Chen, Guanying Feng, Chengzhong Lin, Yang Wang, Zhen Zhang, Yun Zhu, Jinhai Ye, Jiajia Liu, Jun Shi, Xiaomeng Zhou
Published: 202510.1016/j.cell.2025.09.029
Abstract
Whether and how cancer exploits distant organs to escape immune surveillance remains largely unknown. Using clinical data from head and neck squamous cell carcinoma (HNSCC) patients and three murine oral cancer models, we find that cancer cells under…
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