CellActin CytoskeletonMicrofilament ProteinsCryoelectron MicroscopyActin Depolymerizing FactorsActins
Choreography of rapid actin filament disassembly by coronin, cofilin, and AIP1.
Wout Oosterheert, Micaela Boiero Sanders, Oliver Hofnagel, Peter Bieling, Stefan Raunser
Published: 202510.1016/j.cell.2025.09.016
Abstract
Rapid remodeling of actin filament (F-actin) networks is essential for the movement and morphogenesis of eukaryotic cells. The conserved actin-binding proteins coronin, cofilin, and actin-interacting protein 1 (AIP1) act in synergy to promote rapid F…
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