CellHumansParkinson DiseaseMaleMiddle AgedFemale
Phase 1/2a clinical trial of hESC-derived dopamine progenitors in Parkinson's disease.
Jin Woo Chang, Han Kyu Na, Kyung Won Chang, Chan Wook Park, Do-Hun Kim, Sanghyun Park, Chul-Yong Park, Jang Hyeon Eom, Seung Taek Nam, Ki-Sang Jo, Mi-Young Jo, Sung Kyoung Choi, Hye-Jin Hur, Sarang Kim, Minseok Kim
Published: 202510.1016/j.cell.2025.09.010
Abstract
Parkinson's disease (PD) has long been considered an appropriate candidate for cell replacement therapy. We generated high-purity dopaminergic progenitors (A9-DPCs) from human embryonic stem cells and evaluated their safety and exploratory efficacy i…
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