Cell calciumKiller CellsNaturalHumansCalciumCalcium Signaling
Fura-10, unlike fura-2, is suitable for long-term calcium imaging in natural killer (NK) cells without compromising cytotoxicity and can be combined with target cell death analysis.
Lea Kaschek, Joanne Vialle, Gebhard Stopper, Markus D A Hoffmann, Sylvia Zöphel, Johanna Jansky, Nadja Küchler, Gertrud Schäfer, Alina Moter, Philipp Wendel, Frank Neumann, Claudia Schormann, Evelyn Ullrich, Leticia Prates Roma, Carsten Kummerow
Published: 202610.1016/j.ceca.2025.103091
Abstract
There are compelling reasons to opt for primary human natural killer (NK) cells when validating Ca2+ indicators. 1.) NK cells exhibit a high degree of vulnerability to stressors such as indicator loading or light exposure. 2.) The lack of research on…
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