Cell calciumHumansORAI1 ProteinBreast NeoplasmsCalcium ChannelsMCF-7 Cells
Orai1 plays a critical role in Orai3 synthesis and stability in luminal breast cancer cells.
Alvaro Macias-Diaz, Joel Nieto-Felipe, Sandra Alvarado, Francisco J Martin-Romero, Gines M Salido, Isaac Jardin, Tarik Smani, Jose J Lopez, Juan A Rosado
Published: 202510.1016/j.ceca.2025.103089
Abstract
Orai family members are the pore-forming subunits of the Ca2+ release-activated Ca2+ (CRAC) channels that mediate store-operated Ca2+ entry (SOCE), a major mechanism for Ca2+ influx controlled by the filling state of the intracellular Ca2+ stores, th…
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