Current opinion in cell biologySignal Transductionras ProteinsHumansAnimalsActins
Ras signalling at the actin cortex: Coordinating local and global changes to cell morphology.
Joe J Tyler, Helen K Matthews
Published: 202510.1016/j.ceb.2025.102600
Abstract
Ras proteins modulate key cellular signalling pathways and drive excessive proliferation when mutated in cancer. However, they also influence actin cytoskeleton organisation. In the model organism Dictyostelium, domains of active Ras pattern the plas…
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