Current opinion in cell biologyHumansEndocytosisSignal TransductionNeoplasmsAnimals
Driving cancer: Motor and adaptor protein dysregulation in endocytic receptor signalling.
David H Kim, Shreya E Boby, Gregory M I Redpath, Vaishnavi Ananthanarayanan
Published: 202510.1016/j.ceb.2025.102598
Abstract
Receptor tyrosine kinases and other cell surface receptors are tightly regulated by endocytosis, which controls both the duration and spatial organisation of their downstream signalling. In cancers, altered internalisation and trafficking lead to sus…
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