Clinica chimica acta; international journal of clinical chemistry
Increased KIR + CD8+ T cell frequency with impaired cytotoxic potential in systemic lupus erythematosus.
Yun Wang, Xiaofang Bai, Ting Wang, Wei Wei, Rujia Chen, Renren Ouyang, Feng Wang, Hongyan Hou, Shiji Wu
Published: 202510.1016/j.cca.2025.120792
Abstract
OBJECTIVES: Systemic lupus erythematosus (SLE) is a complex autoimmune disease that causes severe immune dysfunctions. Recent insights have identified CD8+ T cells expressing inhibitory killer cell immunoglobulin-like receptors (KIRs) as potentially…
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