Comparative biochemistry and physiology. Toxicology & pharmacology : CBPAnimalsThiamphenicolEnterococcus faeciumCichlidsAnti-Bacterial Agents
Probiotic Enterococcus faecium NCIMB 10415 modulates florfenicol pharmacokinetics, withdrawal time, and hepatic CYP3A activity, potentially lowering antibiotic efficacy in Nile tilapia (Oreochromis niloticus).
Chi-Ming Wu, Yi-Ping Lu, Tirawat Rairat, Yu-Nan Tsai, Channarong Rodkhum, Prapansak Srisapoome, Chi-Chung Chou
Published: 202610.1016/j.cbpc.2025.110438
Abstract
Few studies have examined how probiotics affect drug efficacy in aquaculture. This study investigated impacts of Enterococcus faecium on the pharmacokinetics (PK), tissue residues, and withdrawal time (WDT) of florfenicol (FF) in Nile tilapia. Fish w…
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