Comparative biochemistry and physiology. Toxicology & pharmacology : CBPAnimalsZebrafishAmitriptylineWater PollutantsChemical
Ancestral exposure to amitriptyline disrupts the behavior and gene expression in zebrafish F2 offspring.
Anqi Liu, Kun Chen, Xuchun Qiu, Yuki Takai, Yohei Shimasaki, Yuji Oshima
Published: 202610.1016/j.cbpc.2025.110390
Abstract
Amitriptyline (AMI), a commonly used tricyclic antidepressant, has been identified as a significant pharmaceutical contaminant in aquatic environments. Although parental exposure of zebrafish to AMI has been found to induce changes in the development…
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