Comparative biochemistry and physiology. Part A, Molecular & integrative physiologyAnimalsZebrafishGlucoseLiverGlycogen Synthase
Glycogen synthase 2 knock-out zebrafish exhibit enhanced glucose metabolism in the liver.
Keita Sameshima, Aya Yokose, Rei Yanagida, Yoshiki Sato, Yuta Suzuki, Makoto Kashima, Mayu Inokuchi, Otto Baba, Tatsuki Yoshinaga, Fumiya Furukawa
Published: 202610.1016/j.cbpa.2025.111960
Abstract
The liver is one of the major organs for glycogen storage and is essential for maintaining glucose homeostasis in the whole body. Glycogen synthesis in liver is regulated by the rate-limiting enzyme, glycogen synthase 2 (Gys2). In fish, however, the…
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