Chemico-biological interactions
Thalidezine triggers Cathepsin B-mediated cell death in T-cell lymphoma by disrupting lysosomal function.
Yingjie Qing, Su Xu, Dawei Yang, Jie Liu, Hui Cao
Published: 202610.1016/j.cbi.2026.111932
Abstract
T-cell lymphoma (TCL) is an aggressive malignancy defined by poor prognosis and therapeutic resistance, demanding innovative strategies. Targeting the lysosome to induce cell death has emerged as a powerful anti-cancer strategy, however its potential…
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