Chemico-biological interactionsHumansCell ProliferationAnimalsWnt Signaling PathwayCadmium
ALKBH5 enhances cadmium-induced stemness enrichment and proliferation of colon cancer cells via m6A-dependent regulation of AXIN2 and activation of Wnt/β-catenin signaling.
Jianing Hu, Shuhui Zhu, Xinze He, Bangqi Cen, Zhuangzhuang Xu, Fei Han, Kun Ding, Min Jiang, Yansu Chen, Yefei Huang
Published: 202610.1016/j.cbi.2026.111905
Abstract
Cadmium (Cd) is a carcinogenic heavy metal with a long biological half-life that has been implicated in the development of colorectal cancer (CRC). However, the mechanisms underlying Cd-induced CRC malignancy remain incompletely understood. Cancer st…
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