Chemico-biological interactionsHumansMelatoninYAP-Signaling ProteinsGlycolysisSignal Transduction
Melatonin suppresses glycolysis and coordinately disrupts DNA repair via targeting the YAP1-NAMPT signaling in breast cancer.
Yi-Wen Lai, Cheng-Ying Chu, Zei-Wei Liu, Hsin-Ying Lu, Chi-Ching Lee, Mei-Hsiang Lin, Cheng-Wei Lin
Published: 202610.1016/j.cbi.2026.111900
Abstract
Triple-negative breast cancer (TNBC) is characterized by aggressive behavior and high recurrence rates, contributing to poor prognoses of TNBC patients. However, the lack of appropriate molecular targets limits the effectiveness of current antineopla…
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