Chemico-biological interactionsFemaleHumansPre-EclampsiaPregnancyTrophoblasts
Targeting trophoblast cell mitochondrial dysfunction in preeclampsia via drug repurposing.
Dinara Afrose, Sofía Alfonso-Sánchez, Ashleigh Philp, Philip M Hansbro, Qian Peter Su, Lana McClements
Published: 202610.1016/j.cbi.2025.111883
Abstract
Preeclampsia is a multifactorial pregnancy disorder characterized by the new onset of hypertension and organ damage. Mitochondrial dysfunction is central to preeclampsia pathogenesis leading to placental dysfunction and oxidative stress. This study a…
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