Chemico-biological interactionsStromal Interaction Molecule 1AnimalsHumansGlycosylationEpithelial Cells
STIM1 N-linked glycosylation promotes arsenic-induced malignant phenotype by activating SOCE in bladder epithelial cells.
Pinya Liu, Lei Zhang, Qing Zhou, Zhushan Fu, Shuhua Xi
Published: 202610.1016/j.cbi.2025.111866
Abstract
Epidemiologic research has demonstrated a clear correlation between prolonged exposure to inorganic arsenic and an elevated risk of bladder cancer, but the specific mechanisms are unknown. Calcium ions (Ca2+), as key second messengers, are crucial in…
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