Chemico-biological interactionsHumansOximesLung NeoplasmsIndolesTOR Serine-Threonine Kinases
Multimodal cell death induced by indirubin-3'-oxime through inhibition of Akt/mTOR axis in lung cancer cells.
Na Young Kim, Shalini V Gowda, Kachigere B Harsha, D C Vinay Kumar, Chakrabhavi Dhananjaya Mohan, C S Shivakumara, Kanchugarakoppal S Rangappa, Kwang Seok Ahn
Published: 202610.1016/j.cbi.2025.111851
Abstract
Lung cancer is a major type of malignancy that has contributed to a high mortality rate for many years. Discovering new small molecules with strong cytotoxic effects on lung cancer is crucial for developing new therapies. In this study, we describe t…
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