Chemico-biological interactionsHumansChromiumCadmiumCell Cycle ProteinsDNA
Environmental chromium and cadmium co-exposure induces GADD45A-mediated rDNA instability in human cohorts and cell models.
Yongxin Li, Yao Qin, Chuyan Zhang, Chan Ding, Minqian Feng, Yifan Dou, Xinran Wang, Xia Rao, Xiaoxue Gong, Zhaoqiang Jiang, Jianlin Lou, Huadong Xu
Published: 202510.1016/j.cbi.2025.111789
Abstract
Exposure to heavy metals such as hexavalent chromium [Cr(VI)] and cadmium (Cd) poses a major environmental and occupational health concern due to their widespread presence and genotoxic potential. While the toxicological profiles of individual metals…
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