Chemico-biological interactionsAnimalsCholinesterase InhibitorsMiceButyrylcholinesteraseAcetylcholinesterase
Outlining the A-series of organophosphorus compounds: Cholinesterase inhibition, reactivation, cytotoxicity, and acute toxicity in mice.
Zrinka Kovarik, Dora Kolić, Tena Čadež, Goran Šinko, Petra Tuksar, Tamara Zorbaz, Christophe Curty, Nikolina Maček Hrvat
Published: 202510.1016/j.cbi.2025.111762
Abstract
Given the scarcity of experimental studies on A-series nerve agents (NAs), this paper provides ground-breaking insights and, for the first time, describes the inhibition and reactivation of human acetylcholinesterase (AChE) and butyrylcholinesterase…
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