Cancer letters
Unraveling Stress-Adaptation Pathways in Cancer: Functional Dissection Through CRISPR-Based Genetic Screens.
Fatemeh Mokhles, Mohammad Amin Moosavi, Alvaro Gutierrez-Uzquiza, Guillermo Velasco, Min Li, Marco Cordani
Published: 202610.1016/j.canlet.2026.218246
Abstract
Cancer cells face a hostile microenvironment characterized by hypoxia, nutrient deprivation, endoplasmic reticulum (ER) stress, and oxidative imbalance. To cope with these challenges, they activate an interconnected network of adaptive pathways inclu…
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