Cancer lettersHumansStomach NeoplasmsPrognosisMaleFemale
Extrachromosomal DNA amplifications exhibit distinct molecular characteristics and prognostic implications in gastric cancer.
Seunghyun Kang, Donghyeok Seol, Jieun Lee, Chanmi Bang, Mira Yoo, Soyeon Kim, Sepil An, Hyeongjin Cho, Duyeong Hwang, So Hyun Kang, Young Suk Park, Sang-Hoon Ahn, Hyung-Ho Kim, Eunhee Yi, Sanghyun Kim
Published: 202610.1016/j.canlet.2025.218214
Abstract
Gastric cancer (GC) is characterized by marked molecular heterogeneity that contributes to differential patient outcomes. Focal amplification in form of extrachromosomal DNA (ecDNA) is common in multiple cancer types and is associated with poor patie…
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