Cancer lettersHumansPrecursor T-Cell Lymphoblastic Leukemia-LymphomaRNALong NoncodingDrug Resistance
lncDDR suppresses drug resistance by regulating DNA damage repair through ILF2-YB1 in T-cell acute lymphoblastic leukemia.
Kegan Zhu, Haiyang Zhang, Guoli Li, Suyu Zong, Xue Han, Miaomiao Zhang, Yingchi Zhang, Ming Gao, Wenyu Yang, Zhi Yao, Zhe Liu
Published: 202610.1016/j.canlet.2025.218210
Abstract
T-cell acute lymphoblastic leukemia (T-ALL) is a prevalent hematologic malignancy in pediatric and adolescent populations, characterized by uncontrolled proliferation of immature T lymphocytes. The development of chemoresistance represents a major cl…
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