Cancer lettersAnimalsPancreatic NeoplasmsElectroporationMiceCarcinoma
Irreversible electroporation with intratumoral plant virus immunotherapy induces systemic immunity in a metastatic model of pancreatic cancer.
Debbie K Ledezma, Utsav Joshi, Kim Nguyen-Ta, Himangshu Sonowal, Hana Russo, Isabel G Newton, Nicole F Steinmetz, Rebekah R White
Published: 202510.1016/j.canlet.2025.218074
Abstract
Pancreatic cancer remains highly resistant to immunotherapy, necessitating innovative strategies. This study explores a novel combination of irreversible electroporation (IRE) and plant virus-based nanoparticles to enhance immune responses in pancrea…
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