Brain research bulletinInositol 145-Trisphosphate ReceptorsEndoplasmic Reticulum StressAnimals
Long non-coding RNA THAP7-AS1 interacts with EIF3A and enhances ITPR1 to enhance endoplasmic reticulum stress and endothelial cell pyroptosis in ischemic stroke.
Yini Pan, Hui Chen, Jianhua Xu, Li Zhao, Meifen Yao
Published: 202610.1016/j.brainresbull.2025.111706
Abstract
THAP7-AS1 is a newly discovered long non-coding RNA (lncRNA) whose biological roles in human physiological and pathological processes remain elusive. This study explores the functional impacts of THAP7-AS1 and its interacting molecular cascades in hu…
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