Brain research bulletinAnimalsHippocampusNeurogenesisLipopolysaccharidesMice
Alpha-Bisabolol alleviates LPS-reduced hippocampal neurogenesis and cognitive function by anti-inflammatory action via downregulating MAPK and NF-κB signaling in mice.
Shintae Kim, Su-Bin Seong, Kyung-Joo Seong, Bo-Ram Mun, Won-Seok Choi, Ji-Yeon Jung, Won-Jae Kim
Published: 202610.1016/j.brainresbull.2025.111690
Abstract
Neuroinflammation is a key pathological process contributing to hippocampal neurogenesis impairment and cognitive dysfunction. This study aimed to evaluate the neuroprotective effects of α-Bisabolol (α-Bis), a natural sesquiterpene alcohol, on lipopo…
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