Brain research bulletinAnimalsRatsCA1 RegionHippocampalReperfusion Injury
Cycloastragenol protected hippocampal CA1 neurons by regulating redox homeostasis and alleviated cognitive impairment following cerebral ischemia-reperfusion.
Su Gao, Shihui Zhu, Tianyi Qu, Jiahui Zou, Lida Yin, Xuesong Wang, Xiaokun Yin, Lin Tong, Wei Li
Published: 202610.1016/j.brainresbull.2025.111689
Abstract
OBJECTIVE: This study investigated the neuroprotective effects and mechanisms of cycloastragenol (CAG) on oxidative stress and neurological function in cerebral ischemia-reperfusion injury (CIRI) and oxygen-glucose deprivation/reoxygenation (OGD/R) m…
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