Brain research bulletinHumansMaleFemaleWhite MatterDiffusion Tensor Imaging
Glymphatic dysfunction impairs cognitive function via disrupted white matter network efficiency in primary insomnia: A DTI-ALPS mediation study.
Chen Wang, Tian Zhang, Huizhen Lu, Ziliang Xu, Shengnan Wei, Chaozong Ma, Peng Fang, Yuanqiang Zhu, Fan Guo
Published: 202510.1016/j.brainresbull.2025.111640
Abstract
BACKGROUND: Primary insomnia (PI) is increasingly recognized as a brain network disorder associated with cognitive impairment. Emerging evidence suggests that glymphatic system dysfunction may underlie these deficits by impairing brain clearance mech…
Preview only. Read the full abstract at the source