Brain research bulletinAnimalsMicrogliaAlzheimer DiseaseMalePhysical Conditioning
A role for INPP5D in aerobic exercise-mediated attenuation of microglial activation and neuroinflammation in Alzheimer's disease.
Tao Jiang, Yueyang Zhuang, Jiawei Jian, Junzi Wang, Zhimin Ding, Weilin Liu, Tiecheng Wu, Minguang Yang
Published: 202510.1016/j.brainresbull.2025.111633
Abstract
PURPOSE: Neuroinflammation is closely linked to the pathogenesis of Alzheimer's disease (AD) and the associated deficits in learning and memory. Microglial activation serves as a central mediator of this inflammatory response. While previous studies…
Preview only. Read the full abstract at the source