Brain research bulletinAnimalsFerroptosisMaleMiceInbred C57BL
HDAC2 exacerbates carbon monoxide poisoning-induced brain injury by promoting neuronal ferroptosis through the NEDD4L/ACSL4 axis.
Zuolong Liu, Miao Bian, Jingjing He, Li Pang
Published: 202510.1016/j.brainresbull.2025.111619
Abstract
BACKGROUND: Acute carbon monoxide poisoning (ACMP) induces neuronal damage and ferroptosis, but the role of histone deacetylase 2 (HDAC2) in this process remains unclear. METHODS: Male C57BL/6 mice were exposed to CO to establish ACMP models and trea…
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