Brain research bulletinAnimalsSpinal Cord InjuriesOxidative StressNF-E2-Related Factor 2Mice
Hyperoside alleviates macrophages and microglia-mediated neuroinflammation and oxidative stress through activating PI3K/AKT and Nrf2/HO-1 signaling pathway post spinal cord injury.
Tianyu Zhu, Zhanyang Qian, Zhe Liu, Qinyang Zhang, Haijun Li
Published: 202510.1016/j.brainresbull.2025.111618
Abstract
Spinal cord injury (SCI) is a debilitating and destructive disorder of the central nervous system (CNS), resulting in severe sensory and motor deficits. Secondary injury mechanisms, including neuroinflammation and oxidative stress, play critical role…
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