Brain research bulletinAnimalsBrain InjuriesTraumaticNerve RegenerationMice
NSUN6 promotes neuronal axon regeneration after traumatic brain injury by enhancing HMGB1 expression via m5C modification.
Lei Wang, Quanming Zhou, Jianning Chen, Jianhua Song, Weipeng Hu
Published: 202510.1016/j.brainresbull.2025.111617
Abstract
Traumatic brain injury (TBI) often results in neurofunctional impairments that can be mitigated by promoting axonal regeneration. NOP2/Sun RNA methyltransferase 6 (NSUN6), a 5-methylcytosine (m5C) methyltransferase, has been implicated in TBI recover…
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