Brain research bulletinNeuroprotective AgentsAlzheimer DiseaseMolecular Docking SimulationHumansLipopeptides
Network pharmacology and molecular simulations reveal multi-target neuroprotective potential of Rhamnolipid and Surfactin against Alzheimer's disease.
Shabir Ahmad Usmani, Saqib Ishaq, Abdul Majeed, Qamar Zaman, Abdul Aziz, Sajida Afzal, Raheel Tahir, Ajaz Ahmad, Amin Ullah
Published: 202510.1016/j.brainresbull.2025.111613
Abstract
BACKGROUND: Alzheimer's disease (AD), the primary cause of dementia and lacks potent therapeutic interventions. Natural biosurfactants containing Surfactin and Rhamnolipid, with neuroprotective capability and anti-inflammatory, extend favorable multi…
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