Brain research bulletinAnimalsSpinal Cord InjuriesNF-E2-Related Factor 2FerroptosisProto-Oncogene Proteins c-akt
Dihydroquercetin ameliorates spinal cord injury in rats by modulating the AKT/Nrf2/GPX4 signaling pathway-mediated ferroptosis.
Biao Xu, Zhen-Zhen Liang, Tan Lu, Ming-Ming Zhao
Published: 202510.1016/j.brainresbull.2025.111608
Abstract
Dihydroquercetin (DHQ), a plant-derived flavonoid, possesses significant antioxidant and neuroprotective properties. However, the specific mechanisms underlying its effects on spinal cord injury (SCI) remain unclear. This study aimed to investigate w…
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